ANTI CANCER DRUGS INTRODUCTION
THE ANTI CANCER DRUGS EITHER KILL
CANCER CELLS OR MODIFY THEIR
GROWTH . HOWEVER , SELECTIVITY OF
MAJORITY OF DRUGS IS LIMITED AND
THEY ARE ONE OF MOST TOXIC DRUGS USEDINTHERAPY.
TREATMENT OF MALIGNANT DISEASES WITH
DRUGS IS A RATHER DEVELOPMENT STARTED AFTER 1940
WHEN NITROGEN MUSTARD WAS USED ,
BUT PROGRESS HAS BEEN RAPID , BOTH IN REVEALING
PATHOBIOLOGY OF THE DISEASES AND DISCOVERY
OF NEW DRUGS. IN ADDITION , ATTEMPTS HAVE BEEN
MADE TO DEFINE OPTIMAL COMBINATIONS ,
TREATMENT STRATEGIES AND PATIENT SUPPORT
MEASURES. CANCER CHEMOTHERAPHY IS NOW
OF ESTABLISHED VALUE AND A HIGHLY SPECIALIZED FIELD ;
ONLY THE GENERAL PRINCIPLES AND OUT
LINE WILL BE PRESENTED HERE .
IN ADDITION TO THEIR PROMINENT ROLE IN
LEUKEMIAS AND LYMPHOMAS ,
DRUGS ARE USED IN CONJUNCTION WITH SURGERY ,
RADIOTHERAPY AND IMMUNO THERAPY IN THE COMBINED
MODALITY APPROACH FOR MANY SOLID TUMOURS , SPECIALLY METASTATIC.
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