ROUX en Gastric Bypass  

ROUX en Gastric Bypass

Considered the gold standard in bariatric surgery, a Roux-en-Y gastric bypass is what is known as a combined restrictive and malabsorptive procedure. It is restrictive because the stomach is reduced to a small pouch that can only hold a very small amount of food at a time. It is malabsorptive because a portion of the small intestine is bypassed, reducing the body’s ability to absorb the full amount of calories that are consumed. These two factors, working together, make this procedure extremely effective at helping patients shed large amounts of excess weight. We perform laparoscopic gastric bypass at our practice serving Fort Worth, Arlington, and the entire Dallas region so that patients can enjoy the benefits of bariatric procedures without the discomfort of open surgery.

  • Laparoscopic Roux-en-Y Gastric Bypass
  • Benefits
  • Risks

Laparoscopic Roux-en-Y Gastric Bypass

Roux-en-Y gastric bypass involves the separation of the stomach into two sections. The small upper portion can collect and digest food, but only in very small quantities. This small stomach pouch is then connected to the middle portion of the small intestine. The remainder of the stomach and upper segment of the small intestine are left in place, but bypassed. These bypassed segments are responsible for producing certain necessary digestive acids and proteins, which they will continue to do, even though food will no longer pass through them.

Traditionally, Roux-en-Y has been performed as an open procedure, involving a significant amount of pain, a long recovery time, and substantial surgical risk. Using laparoscopic techniques, we can perform the same gastric bypass procedure at our Dallas, Arlington, and Fort Worth-area practice while using only five small incisions. This results in a much shorter and easier recovery and virtually no noticeable scarring.

Benefits

There are many reasons why this procedure has become the leader in the field of bariatrics. First and foremost, it is extremely effective for the majority of patients. It does not involve the use of any implanted device, like gastric banding, and because nothing is removed, it is technically reversible, although this is strongly advised against.

People who have undergone gastric bypass surgery have experienced reduction or resolution of such conditions as type 2 diabetes and acid reflux disease, even before a significant amount of weight is lost. As the weight comes off, additional benefits include decreased hypertension, increased energy, reduced pressure on the joints, and improved confidence.

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Risks

Gastric bypass surgery, like all surgery, carries an inherent amount of risk. Although patients who are obese present with a more complicated medical history, bariatric surgery is actually statistically safer than many of the common surgical procedures performed every day in the United States. At Minimally Invasive Bariatrics, we thoroughly discuss all of the potential risks with each patient prior to surgery.

After the surgery is complete, some side effects associated with Roux-en-Y gastric bypass could still occur. Due to the malabsorptive aspect of the procedure, some patients experience vitamin or nutrient deficiencies. This can be avoided by carefully following the dietary guidelines provided by our practice and taking the recommended vitamin supplements. Many patients have also experienced an extremely uncomfortable side effect known as “dumping syndrome,” which is caused by the stomach emptying food into the intestine too quickly. This is most often triggered by the consumption of high-fat or sugary foods, so once again, following a proper Post-bariatric diet will minimize the chances of this condition appearing.

Bariatric surgery in Arlington  

Minimally Invasive Bariatrics is committed to providing our patients with the best care possible. As part of this commitment, we offer a wide range of procedures, which we perform using only the most advanced minimally invasive methods available.

Often called the gold standard in bariatric surgery techniques, Roux-en-Y gastric bypass is a well-established weight loss surgery procedure that involves permanently altering the path of the upper digestive system. Learn more about Roux-en-Y surgery.

The LAP-BAND® System is a popular alternative to the classic gastric bypass surgery, as it restricts the amount of food that can be consumed without making permanent structural changes to the digestive system. Find out how the LAP-BAND® System and other gastric banding options, such as the REALIZE™ Band, work.

The sleeve gastrectomy is a relatively new form of bariatric surgery offered at Minimally Invasive Bariatrics in Arlington, Dallas, and the Fort Worth area. It involves reducing the size of the stomach as well as the stomach's ability to produce certain appetite-inducing hormones. Read more about sleeve gastrectomy.

StomaphyX™ allows surgeons to access the stomach through the esophagus, eliminating the need for incisions altogether. This results in significantly shorter healing times and no visible scars whatsoever. Learn more about StomaphyX™ and whether this remarkable technology might be right for you.

ANTI CANCER DRUGS INTRODUCTION  


THE ANTI CANCER DRUGS EITHER KILL
CANCER CELLS OR MODIFY THEIR
GROWTH . HOWEVER , SELECTIVITY OF
MAJORITY OF DRUGS IS LIMITED AND
THEY ARE ONE OF MOST TOXIC DRUGS USEDINTHERAPY.
TREATMENT OF MALIGNANT DISEASES WITH
DRUGS IS A RATHER DEVELOPMENT STARTED AFTER 1940
WHEN NITROGEN MUSTARD WAS USED ,
BUT PROGRESS HAS BEEN RAPID , BOTH IN REVEALING
PATHOBIOLOGY OF THE DISEASES AND DISCOVERY
OF NEW DRUGS. IN ADDITION , ATTEMPTS HAVE BEEN
MADE TO DEFINE OPTIMAL COMBINATIONS ,
TREATMENT STRATEGIES AND PATIENT SUPPORT
MEASURES. CANCER CHEMOTHERAPHY IS NOW
OF ESTABLISHED VALUE AND A HIGHLY SPECIALIZED FIELD ;
ONLY THE GENERAL PRINCIPLES AND OUT
LINE WILL BE PRESENTED HERE .
IN ADDITION TO THEIR PROMINENT ROLE IN
LEUKEMIAS AND LYMPHOMAS ,
DRUGS ARE USED IN CONJUNCTION WITH SURGERY ,
RADIOTHERAPY AND IMMUNO THERAPY IN THE COMBINED
MODALITY APPROACH FOR MANY SOLID TUMOURS , SPECIALLY METASTATIC.

harmonalfactors-obesity  

Obesity is a global epidemic resulting from sedentary life styles, improved socioeconomic conditions and availability of processed high caloric foods and soft drinks in industrialized society

Behavioural and dietary changes are the initial therapeutic strategies, wt loss drugs should be used with caution especially herbal preparations that combine ephedra alkaloids and caffenine, because there are serious potential adverse reactions.

Measurement of fat accumulation
• Ex or wt in relation to ht (BMI)
• Skin fold measurements
• Various body circumference particularly the ratio of waist to hip circumference.
BMI expressed in kilograms per sq meter is closely related to body fat
BMI of 25 kg/m2 is considered normal
30 kg/m2 is – obese
2529.9 over weight
Other techniques for measuring body composition include under water weighing (densitometry), CAT, MRI and Dexa scanning.

CENTRAL OR VISCERAL OBESITY
Fat accumulates in trunk and in the abd cavity is associated with a much higher risk for several diseases than in excess accumulation of fat diffusely in subcutaneous tissue.

Obesity is a disorder of energy balance when food derived energy chronically exceeds expenditure the excess calories are stored as triglycerides in adipose tissue.
Three components of this system
1.The afferent system which generates humoral signals from adipose tissue (leptin) pancreas (insulin) and stomach (gherlin)
2.Central processing unit located primarily in the hypothalamus – interprets the afferent signals.
3.Effector system which carries out orders from the hypothalamic nuclei in the form of feeding behaviour.
•Gherlin is a short term mediator à increase sharply before every meal and fall promptly when the stomach is filled.
•Success of gastric bypass surgery is massively obese indiviuals may relate more to associated suppression of gherlin levels.
•Leptin has a more important role than insulin in CNS
•Adipocytes communicate with hypothalamic centers that control apeptite and energy expenditure by secreting leptin a member of cytokine family.
•Net effect of leptin therefore is to reduce food intake and promote energy expenditure.
•Hence over a period of time energy stores are reduced and wt is lost in turn reduces the circulating levels of leptin and now equilibrium reached.
•Decrease leptin levels the anabolic circuits are relieved of inhibition and catabolic circuits are not activated, resulting in net gain of weight.

GENETICS OF OBESITY
Disorder of multifactorial etiology
• BMI in monozygotic twins versus dizygotic
• Leptin – energy hemostasis – OB gene
• Leptin – melanocortin circuit – arcute nucleus of hypothalamus

Two major types of neurons that bear lepin receptors
Oraxogenic – apeptite stimulating neurotransmitters
Leptin – decrease NPY / agouti – related peptide
POMC / CART Neurons
Leptin – sensitive à POMC / CART
Anorexigenic neuropeptides alpha – melanocyte – stimulating hormone (alpha MSH) cocaine and amphetamine – related (CART)
Both are the products of POMC – catabolic effects.
NPY / AgRP and POMC / CART neurons – first order neurons.
The neurotransmitters produced by (NPY / AgRP and alpha MSH)
2nd order neurons à efferent system



Lung Cancers in Women  



Lung cancer strikes 900,000 men and 330,000 women yearly.



Among men, smoking causes more than 80 per cent



of lung cancer cases. In women,



smoking is the cause of 45 per cent of all lung cancer worldwide,



but more than 70 per cent in North America and Northern Europe.



In both men and women, the incidence of lung cancer is low before age 40,


and increases up to age 70 or 75.



The rise in female smoking prevalence is a



major public health concern.



In the US, more women die from smoking-induced



lung cancer than from breast cancer and in some Nordic countries,




including Iceland and Denmark,



female lung cancer deaths have begun to



outnumber male tobacco victims.



Considering that in several European countries



up to 50 per cent of young women are now regular smokers,



this will cause a disease burden that significantly



reduces women’s health in decades to come.

Cancer prevention:  


Cancer prevention:


a healthy diet can help!

Epidemiological studies indicate that the frequent consumption
of fruit and vegetables may reduce the risk of developing cancers of epithelial origin, including
carcinomas of the pharynx, larynx, lung, oesophagus, stomach,
colon and cervix. Recent data from the European
Prospective Investigation into Cancer and Nutrition (EPIC
suggests that a daily consumption of 500 grams (1.1. lbs.)
of fruits and vegetables can decrease incidence of cancers
of the digestive tract by up to 25 per cent.
The report also says that given the multi-faceted
impact of diet on cancer, many countries should encourage
consumption of locally produced vegetables,
fruit and agricultural products, and avoid the adoption of
Western style dietary habits. IARC says that such actions
would have health benefits beyond cancer,
since other common non-communicable diseases,
notably cardiovascular disease and diabetes,
share the same lifestyle-related risk factors.
Early detection – the best strategy second to
primary prevention The best possible prevention against
cancer remains the avoidance of exposure to
cancer-causing agents: this is called primary prevention
(eg tobacco, industrial carcinogens, etc).


There is sound evidence that the recent decline in cancer mortality
observed in several countries is to a significant
extent due to early detection. Responsible for
this success are not only improvements in imaging
(mammography, magnetic resonance (MR) and
computed tomography (CT) imaging),
but also a higher degree of disease awareness and
educational programmes on typical early symptoms.

Most successful so far has been the early detection
of cervical cancer by cytology and of breast cancer by mammography.

A recent analysis by an IARC Working Group
concluded that under trial conditions, mammography
screening may reduce breast cancer mortality
by 25-30 per cent and that in nation-wide screening


programmes a reduction by 20 per cent appears feasible.
There is also emerging evidence that prostate
cancer screening by assessment of serum PSA levels may
result in lower mortality rates but management
of early lesions is still very invasive. For colon cancer,
colonoscopy is considered the gold standard although

its application in population-based screening

programmes would require considerable medical resources.

Nutrition and cancer - good news  

Nutrition and cancer – the good news

Stomach cancer is among the most common malignancies worldwide,
with some 870,000 cases every year, and 650,000 deaths.
About 60 per cent of cases occur in developing countries,
with the highest incidence rates coming in Eastern Asia,
the Andean regions of South America and Eastern Europe.
The good news is that stomach cancer is declining world-wide,
in some regions almost dramatically.
In Switzerland and neighbouring European countries,
the mortality fell by 60 per cent within one generation.
If this trend continues, stomach cancer may in some
world regions become a rare disease during the next 30 years.
The main reason for this welcome development
is the invention of the refrigerator,
allowing fish and meat preservation without salting.
The drop in incidence and mortality rates is therefore
particularly impressive in Nordic countries
in which fish consumption is traditionally high, e.g. Iceland.
In populations that still prefer salty food,
e.g. Portugal and Brazil (salted cod, bacalao),

Japan and Korea (salted pickles and salad),

stomach cancer rates are still high but have
also started to decline significantly.
An additional factor contributing to this trend is the availability
in many countries of fresh fruit and vegetables throughout the year.

cancer introductiion  


There are more than 100 types of cancers;


any part of the body can be affected


In 2005, 7.6 million people died of cancer -


13% of the 58 million deaths worldwide



More than 70% of all cancer deaths occur


in low and middle income countries.


Worldwide, the 5 most common types of cancer that


kill men are (in order of frequency):
lung, stomach,



liver, colorectal and oesophagus



Worldwide, the 5 most common types of cancer


that kill women are (in the order of frequency):


breast, lung, stomach, colorectal and cervical


Tobacco use is the single largest preventable


cause of cancer in the world

One fifth of all cancers worldwide are caused by a


chronic infection, for example human papillomavirus


(HPV) causes cervical cancer and hepatitis B virus


(HBV) causes liver cancer.


A third of cancers could be cured if detected

early and treated adequately


All patients in need of pain relief could be helped if current


knowledge about pain control and palliative care were applied


30% of cancer could be prevented,


mainly by not using tobhaving a healthy diet,

being physically active and preventing

infections that may cause canceracco,


having a healthy diet, being physically

active and preventing infections


that may cause cancer

BREAST CANCER  




It is one of the commonest cause of death in



many developed countries in middle aged women.



risk factors:



1)age:

1) it is most common in beetween age of 35 and 50 and



uncommon below the age of 35.



2)family history



1)the risk is high in those with a positive family history of breast cancer.



3)socio-economic status



it is common in higher socio-economic group.



4)others



1)early menarcheand late menopause



2)using oral contraceptives



3)elevated levels of estrogen and progesterone.



prevention



1)primary prevension:

1)eliminate the risk factors



2)promation of cancer education .



3)the average age at menarche can be increased through



a reduction in childhood obesity and increase in strenuous physical activity



2)secondary prevention



1)breast screening leads to early diagnosis of breast cancer.



2)after confermation start treament



3)detect recurrence as early as possible.



OBESITY- CONTROL  


PREVENTION AND CONTROL OF OBESITY

Prevention of obesity should begin in early childhood.

obesity is harder to treat in adults than it is in childran .

the main aim is weight redution, it is achieved by

1)Dietery changes

2)increased physical activity

3)others

1)DIETARY CHANGES:

1)Energy dence food such as simple carbohydrates andfat should be reduced.

2)the fibre content in diet should be increased.

3)adequate levels of essential nutrients in low energy diet should be ensured.

4)the reducing diet should be as close as possible to existing nutritional patterns.

5)the most basic consideration is that the food energy intake shouldnot be

greater than what ia necessary for energy expenditure.

2)increased physical activity

1)it is the important part opf weight reducing programme.

2)regular physical exercise is the key to an increased energy expenditure

3)others

1)appetite suppressing drugs have been tried in ythe control of obesity.

2)surgical treatment (gastric bypass,gasroplasty,jaw-wiring to eleminate to eating of solid food)


HAZARDS OF OBESITY

Relative risk of health problems associated with obesity

Greatly increased:

1)Gallbladder diseases

2)Dyslipidaemia

3)Insulin resistance

4)Breathlessness

5)Sleep apnea

6)NIDDM

Moderately increased

1)CHD

2)HYPERTENSION

3)Osteoarthritis

4)Hyperuricaemia

5)Gout

Slightly increased

1)Cancer(Breast and endometrial)

2)Reproductive hormone abnormalities

3)Polycystic ovary syndrome

4)Impaired fertility

5)Low back pain

6)Increased risk of anaesthesia complications

7)Fetal defects associated with maternal obesity.



seizure disorder  

SEIZURE

Caused by transient, paroxymal and synchronous discharge

of groups of Neurons in the brain


Clinical manifestations depends on the location and number

of neurons involved, in the seizure discharge and its duration.

May be

1.Transient or

2.Permanent (Epilepsy)

Classification of Epileptic seizures

• Partial

• Generalized

• Unclassified

PARTIAL

-Simple partial seizures (consciousness not impaired)

- Complex partial seizures (consciousness impaired)

- Partial seizures evolving to generalized seizures (Tonic, clonic or tonic-clonic)


GENERALIZED SEIZURES
(Convulsive or non convulsive)

•Absence seizures

•Myoclonic seizures

•Clonic seizures

•Tonic seizures

•Clonic tonic seizures

•Atomic seizures.


DRUGS USED IN DIFFERENT DISORDERS

Partial Seizures

- Carbamazepine

- Phenyotin and

- valproate

Generalized seizures

- Carbamazepine

- Phenyotin
- Valproate

- Barbiturates

- Gabapentin or

- Lamotrigine

Generalized non seizures

- Ethosuximide (or)

- Valproate

SIDE EFFECTS

Depression of cerebral function with symptoms of sedation

- Diploma

- Persistent or fluctuation ataxia

Dyskinesias of the tongue, face and limbs

- Mild sensory neuropathy

- Altered peripheral nerve function

•Hepatic failure

• Pancreatitis

• Mild anaemia to aplastic anaemia

• Depress circulating platelets

• Skin rashes

• SLE

• Seroderma and

• Sjogrens syndrome

• Steven johnsons syndrome

STATUS EPILEPTICUS

Def : Continuous seizure activity or two or more seizures

occurring in sequence without recovery of consciousness between the seizures

PHARMACOLOGIC MANAGEMENT OF STATUS EPILEPTICUS

1.Lorazepam / Diazepam – 0.1 mg / kg I.V at 2 mg/ min

2.Phenytoin – 20mg / kg I.V at 50mg / min or fosphenytoin 20mg/kg IV at 150mg/min

3.Phenyotin or fosphenytoin additional 5-10 mg/kg

4.Phenobarbitol 20mg/kg I.V at 50-75 mg/min

5.Phenobarbitol – additional 5-10mg/kg

6.Anaesthesia with propofol or midazolam

OTHER AREAS OF TREATMENT

•Exclude hypoglycemia

•Tracheal intubation

•ABG

•Hyperthermic management

Management of Anaesthesia for seizure disorders

Consider impact of drugs on organ function

- Coagulation

- Response to anaesthetic drugs.

TONSILITIS  



DEFINITION:

It is the inflammation of the tonsils.



TYPES:

ACUTE

Sub acute

Chronic

ACCUTE TONSILITIS:

It is the acute inflammation of the tonsil.

CLASSIFICATION

1)Acute catarrhal / superficial

2)Acute follicular

3)Acute parenchymatous

4)Acute membranous
AETIOLOGY:

Age :
CHILD

Sex :
BOTH

Predisposing factors:

Preexisting chronic tonsillitis

Post nasal discharge due to chronic tonsillitis

Preexisting infections of URT

General lowering of resistance

Ingestion of cool drinks

Infection can be contracted from others


CAUSATIVE ORGANISMS :


Haemolytic streptococcus- most common

Staphylococci

Pneumococci

H.infuenzae

Diptheriods
SYMPTOMS:

Sore throat.

Difficulty in swallowing

Fever.

Otalgia

Foul breath

Constitutional symptoms:

Headache

General body aches

Malaise

Constipation

Thick & muffled voice
SIGNS:

Foetid breath & coasted tongue.

Hyperaemia of pillars, soft palate& uvula

Follicular: Red & swollen tonsils with yellowish purulent material at crypts

Membranous: Whitish membrane on the medial surface can be wiped off

Parenchymatous: Enlarged & congested tonsils with oedema of uvula & soft palate.

Tender & enlarged jugulodigastric lymph nodes.

TREATMENT:

Bed rest & soft diet.

Analgesics & antibiotics to be given.

Warm saline gargles are soothing.

Lozenges with local anaesthetic action.

Antimicrobial therapy

Tonsillectomy for recurrent attack.

Note: rash appear if amoxycillin or ampicillin are given

COMPLICATIONS:

Acute otitis media

Peritonsillar abscess

Parapharyngeal abscess

Cervical abscess

Rheumatic fever

Acute glomerulonephritis

Subacute bacterial endocarditis

Acute nephritis

HOW DO WE TASTE THE FOOD?  




PHYSIOLOGY OF TASTE


.Taste is one of the special senses,

sensed by tongue through taste buds.

.There are 4 primary taste sensations


SALT,SWEET,BITTER,SOUR and umami

.Taste buds are present on papillae


Circumvallate papillae present


on the posterior part of the tongue

Foliate papillae present on the lateral


surface of the tongue and Filiform

papillae on the anterior surface of the tongue

.

ACNE  




ACNE VULGARIS



It is a self limited disorder



It is seen mainly in teenagers and young adults



PATHOLOGY

Mainly by increase in sebum production by sebaceous glands after puberty.

small cysts called comedons,form in hair follicles due to blockage of follicular orifice

by retention of sebam and keratinous material.

Proprionobacterium acnes bacteria with in comedones release free fatty acids from sebum, causes inflammation within the cysts, and results in rupture of the cyst wall.



Clinical features

the clinical hallmark of acne vulgaris is the comedone,2types

1)closed (whitehead)

2)open(blackhead)

Closedcomedones-

they appear as 1 to 2mm pebbly white papules

they are the precursors of inflammatory lesions of acne vulgaris

open comedones

these have a large dilated follicular orifice

and filled with easily expressible oxidized,darkened,oily debries

comedones are usually accompanied by inflammatory lesions

1)papule

2)pustules

3)nodules

sites mainly seen

the earlist lesions seen on the forehead subsequently more typical inflammatory

lesions on the cheek,nose and chine.

most common locations for acne is face ,uncommons sites are chest and back.



factors influence acne

1)glucocorticoids,applied topically or adminstered systemically in high doses may

elicit acne

2)systemic medications such as lithium,isoniazid,halogens,phenytoin
and phenobarbital may produce or aggravate preexisting acne.

3)application of comedogenic topical agents



treatment

it may be treated with either localor systemic medications

Areas affected with acne should be kept clean.



topical agents-

prevent formation of comedones

1)retinoic acid

2)benzoyl peroxide

3)salicylic acids



topical antibacterial agents

DEVIATED NASAL SEPTUM  


THE NASAL SEPTUM IS THAT PART OF

THE NOSE WHICH SEPARATES THE TWO

AIRWAYS&NOSTRILS. A DEVIATED NASAL

SEPTUM IS WHEN THERE THE SHIFT FROM

THE MIDDLE OR CENTRAL POSITION

AETIOLOGY:

1) TRAUMA: USUALLY IN CHILDHOOD , MAY EVEN BE DURING DELIVERY.

2) CONGENITAL DISORDERS 3) HEREDITARY DISORDERS

4) RACIAL PREDISPOSITION

TYPES OF DNS:

1) ANTERIOR DISLOCATION 2) C-SHAPED DEFORMITY 3) SPURS

4) SEPTALTHICKENING 5) S-SHAPED DEFORMITY

CLINICAL FEATURES:

1) NASAL OBSTRUCTION 2) COTTLE'S TEST 3) MUCOSAL CHANGES

4) NEUROLOGICAL CHANGES

SYMPTOMS:

THE SYMPTOMS CAUSED BY SEPTAL DEVIATIONS AREENTIRELY RESULTS OF THEIR

EFFECTS ON NASALFUNCTION. THE DOMINANT EFFECT BEING NASAL

OBSTRUCTION,BUT THIS IS RARELY SEVERE ENOUGH TO CAUSE ANOSMIA

. SIGNS:

1)HEADACHE 2) SINUSITIS 3) BLEEDING FROM THE NOSE 4) EXTERNAL DE FORMITY

5) MIDDLE EAR INFECTION 6) NOISY BREATHING DURING SLEEP

COTTLE'S CLASSIFICATION:

1) SIMPLE DEVIATION 2) OBSTRUCTION 3) IMPACTION

TREATMENT :

MEDICAL MANAGEMENT
1) ANTIBIOTICS 2) ANTIHISTAMINS 3)ANTI INFLAMMATORY DRUG

4) NASAL DECONGEST DROPS

SURGICAL MANAGEMENT :

1)SEPTOPLASTY 2) SUBMUCOUS RESECTION(SMR)

H
OW TO AVOID DNS :
1) USE APPROPRIATE SAFETY EQUIPMENT DURING SPORTS .

2)USE A HELMET WHEN RIDING A BIKE OR ROLLER SKATING

3) FASTEN UR SEAT BELT WHEN DRIVING