Health is Wealth

The international neuroblastoma staging system (INSS)

Stage 1 Localized tumour with complete gross excision, with or without microscopic residual disease; representative
ipsilateral lymph nodes negative for tumour microscopically (nodes attached to and removed with the primary
tumour may be positive).
Stage 2A Localized tumour with incomplete gross excision; representative ipsilateral nonadherent lymph nodes negative for tumour microscopically.
Stage 2B Localized tumour with or without complete gross excision, with ipsilateral nonadherent lymph nodes positive for tumour. Enlarged contralateral lymph nodes must be negative microscopically.
Stage 3 Unresectable unilateral tumour infiltrating across the midline (vertebral column) with or without regional lymph node involvement; or localized unilateral tumour with contralateral regional lymph node involvement; or midline tumour with bilateral extension by infiltration (unresectable) or by lymph node involvement.
Stage 4 Any primary tumour with dissemination to distant lymph nodes, bone, bone marrow, liver, skin and/or other organs (except as defined for stage 4S).
Stage 4S Localized primary tumour (as defined for stage 1, 2A or 2B), with dissemination limited to skin, liver and/or bone marrow (limited to infants <1 year of age).